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Fgf18tm1Tri
Targeted Allele Detail
Summary
Symbol: Fgf18tm1Tri
Name: fibroblast growth factor 18; targeted mutation 1, Toru Imamura
MGI ID: MGI:5425911
Synonyms: Fgf18flox
Gene: Fgf18  Location: Chr11:33067430-33097400 bp, - strand  Genetic Position: Chr11, 19.21 cM
Alliance: Fgf18tm1Tri page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:184628
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the neo cassette. (J:184628)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgf18 Mutation:  10 strains or lines available
References
Original:  J:184628 Kimura-Ueki M, et al., Hair cycle resting phase is regulated by cyclic epithelial FGF18 signaling. J Invest Dermatol. 2012 May;132(5):1338-45
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory