Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ddah1tm1.1Yjch
Name:	dimethylarginine dimethylaminohydrolase 1; targeted mutation 1.1, Yingjie Chen
MGI ID:	MGI:5424370
Synonyms:	DDAH1-
Gene:	Ddah1  Location: Chr3:145464447-145600032 bp, + strand  Genetic Position: Chr3, 70.63 cM, cytoband H3
Alliance:	Ddah1tm1.1Yjch page

Germline Transmission:	Earliest citation of germline transmission: J:182373
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exon 4 was deleted from Ddah1tm1Yjch by germline cre-mediated recombination. No encoded protein was detected in tissue samples from kidney, brain, liver and lung of homozygous animals. (J:182373)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ddah1 Mutation:	18 strains or lines available

Original:	J:182373 Hu X, et al., Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine. Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1540-6
All:	6 reference(s)