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Gene Expression Data
Assay Details
Assay
Reference: J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
Assay type: RNA in situ
MGI Accession ID: MGI:5423882
Gene symbol: Me1
Gene name: malic enzyme 1, NADP(+)-dependent, cytosolic
Probe: EH604 probe 617
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Cryosections of fresh frozen material were fixed in 4% paraformaldehyde for 20 min. before further processing. A tyramide-biotin/streptavidin amplification step was included in the in situ hybridization procedure. These data were downloaded from GenePaint.org on 1/30/12.
Results
Specimen EH604; Specimen C2412: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nervous system Strong Regionally restricted Embryo_C2412_5_4B
TS22: central nervous system Strong Regionally restricted Embryo_C2412_5_4B
TS22: telencephalon Weak Regionally restricted Embryo_C2412_5_3D
TS22: cerebral cortex Weak Regionally restricted Embryo_C2412_5_3D
TS22: neocortex Weak Regionally restricted Embryo_C2412_5_3D
TS22: olfactory cortex Weak Regionally restricted Embryo_C2412_5_3D
TS22: main olfactory bulb Weak Regionally restricted Embryo_C2412_5_3D
TS22: piriform cortex Absent
TS22: hippocampus Absent
TS22: basal ganglia Absent
TS22: corpus striatum Absent Expression was not detected in the corpus striatum (lateral ganglionic eminence).
TS22: basal forebrain Absent
TS22: amygdala Absent
TS22: telencephalon septum Absent
TS22: pallidum Absent Expression was not detected in the pallidum (medial ganglionic eminence).
TS22: diencephalon Weak Regionally restricted Embryo_C2412_5_3B
TS22: thalamus Weak Regionally restricted Embryo_C2412_5_3B
TS22: hypothalamus Absent
TS22: midbrain Strong Regionally restricted Embryo_C2412_5_4A
TS22: pretectum Absent
TS22: superior colliculus Weak Regionally restricted Embryo_C2412_5_3C
TS22: inferior colliculus Absent
TS22: midbrain tegmentum Strong Regionally restricted Embryo_C2412_5_4A
TS22: hindbrain Strong Regionally restricted Embryo_C2412_5_3C
TS22: cerebellum Absent
TS22: pons Moderate Regionally restricted Embryo_C2412_5_3C
TS22: medulla oblongata Strong Regionally restricted Embryo_C2412_5_3C
TS22: spinal cord Strong Regionally restricted Embryo_C2412_5_4B
TS22: choroid plexus Moderate Regionally restricted Embryo_C2412_5_3B
TS22: meninges Moderate Regionally restricted Embryo_C2412_5_1C
TS22: peripheral nervous system Moderate Ubiquitous Embryo_C2412_5_2C
TS22: cranial ganglion Moderate Ubiquitous Embryo_C2412_5_2C
TS22: dorsal root ganglion Moderate Ubiquitous Embryo_C2412_5_2C
TS22: eye Moderate Regionally restricted Embryo_C2412_5_1B
TS22: retina Absent
TS22: lens Moderate Regionally restricted Embryo_C2412_5_1B
TS22: cornea Absent
TS22: optic nerve Absent
TS22: nose Absent
TS22: olfactory epithelium Absent
TS22: ear Absent
TS22: inner ear Absent
TS22: cochlea Absent
TS22: inner ear labyrinth Absent
TS22: middle ear Absent
TS22: alimentary system Moderate Regionally restricted Embryo_C2412_5_4D Expression was detected in the digestive system.
TS22: intestine Absent
TS22: salivary gland Absent
TS22: tongue Absent
TS22: tooth Moderate Regionally restricted Embryo_C2412_5_4D
TS22: palatal shelf Absent
TS22: esophagus Absent
TS22: stomach Absent
TS22: liver Moderate Regionally restricted Embryo_C2412_5_4D
TS22: respiratory system Moderate Regionally restricted Embryo_C2412_5_1D
TS22: pharynx Absent
TS22: larynx Absent
TS22: trachea Absent
TS22: main bronchus Absent
TS22: lung Moderate Regionally restricted Embryo_C2412_5_1D
TS22: urinary system Strong Regionally restricted Embryo_C2412_5_2C Expression was strong in the genito-urinary system.
TS22: metanephros Absent
TS22: ureter Absent
TS22: bladder Moderate Regionally restricted Embryo_C2412_5_4D
TS22: urethra Weak Regionally restricted Embryo_C2412_5_4D
TS22: reproductive system Strong Regionally restricted Embryo_C2412_5_2C
TS22: genital tubercle Moderate Regionally restricted Embryo_C2412_5_5A
TS22: gonad Strong Ubiquitous Embryo_C2412_5_2C
TS22: gland Strong Regionally restricted Embryo_C2412_5_5B Expression was strong in the endocrine system.
TS22: thyroid gland Absent
TS22: pituitary gland Moderate Regionally restricted Embryo_C2412_5_3D
TS22: pancreas Absent
TS22: adrenal gland Strong Ubiquitous Embryo_C2412_5_5B
TS22: cardiovascular system Strong Regionally restricted Embryo_C2412_5_3C
TS22: heart Moderate Regionally restricted Embryo_C2412_5_3C
TS22: heart atrium Absent
TS22: heart ventricle Moderate Regionally restricted Embryo_C2412_5_3C
TS22: blood vessel Weak Regionally restricted Embryo_C2412_5_4A
TS22: hemolymphoid system Absent Expression was not detected in the immune system.
TS22: spleen primordium Absent
TS22: thymus primordium Absent
TS22: appendicular skeleton Absent Expression was not detected in the skeleton (limbs, shoulder, hip).
TS22: musculature Absent
TS22: face Moderate Regionally restricted Embryo_C2412_5_1D Expression was detected in the face/soft tissues.
TS22: facial bone primordium Weak Regionally restricted Embryo_C2412_5_4B
TS22: cranium Moderate Regionally restricted Embryo_C2412_5_1D Expression was detected in the skull (base and vault).
TS22: axial skeleton Absent
TS22: tail Moderate Regionally restricted Embryo_C2412_5_4D
TS22: forelimb Moderate Regionally restricted Embryo_C2412_5_1D
TS22: hindlimb Moderate Regionally restricted Embryo_C2412_5_1D
TS22: integumental system Absent
TS22: skin Absent
TS22: hair Absent
TS22: vibrissa follicle Absent Expression was not detected in whisker follicle.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory