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Gene Expression Data
Assay Details
Assay
Reference: J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
Assay type: RNA in situ
MGI Accession ID: MGI:5423782
Gene symbol: Mthfd1
Gene name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
Probe: ES682 probe 645
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Cryosections of fresh frozen material were fixed in 4% paraformaldehyde for 20 min. before further processing. A tyramide-biotin/streptavidin amplification step was included in the in situ hybridization procedure. These data were downloaded from GenePaint.org on 1/30/12.
Results
Specimen ES682; Specimen S294: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nervous system Strong Regionally restricted Embryo_S294_6_3A
TS22: central nervous system Strong Regionally restricted Embryo_S294_6_3A
TS22: telencephalon Strong Regionally restricted Embryo_S294_6_3C
TS22: cerebral cortex Strong Regionally restricted Embryo_S294_6_3C
TS22: neocortex Strong Regionally restricted Embryo_S294_6_3C
TS22: olfactory cortex Strong Regionally restricted Embryo_S294_6_5A
TS22: main olfactory bulb Strong Regionally restricted Embryo_S294_6_5A
TS22: piriform cortex Absent
TS22: hippocampus Strong Regionally restricted Embryo_S294_6_3C
TS22: basal ganglia Strong Regionally restricted Embryo_S294_6_3C
TS22: corpus striatum Strong Regionally restricted Embryo_S294_6_2B Expression was strong in the corpus striatum (lateral ganglionic eminence).
TS22: basal forebrain Absent
TS22: amygdala Absent
TS22: telencephalon septum Strong Regionally restricted Embryo_S294_6_3C
TS22: pallidum Strong Regionally restricted Embryo_S294_6_3C Expression was strong in the pallidum (medial ganglionic eminence).
TS22: diencephalon Absent
TS22: thalamus Absent
TS22: hypothalamus Absent
TS22: midbrain Strong Regionally restricted Embryo_S294_6_3A
TS22: pretectum Absent
TS22: superior colliculus Moderate Regionally restricted Embryo_S294_6_3C
TS22: inferior colliculus Strong Regionally restricted Embryo_S294_6_3A
TS22: midbrain tegmentum Moderate Regionally restricted Embryo_S294_6_4A
TS22: hindbrain Strong Regionally restricted Embryo_S294_6_3C
TS22: cerebellum Strong Regionally restricted Embryo_S294_6_4A
TS22: pons Strong Regionally restricted Embryo_S294_6_3C
TS22: medulla oblongata Strong Regionally restricted Embryo_S294_6_3C
TS22: spinal cord Weak Regionally restricted Embryo_S294_6_3B
TS22: choroid plexus Absent
TS22: meninges Absent
TS22: peripheral nervous system Absent
TS22: cranial ganglion Absent
TS22: dorsal root ganglion Absent
TS22: eye Strong Regionally restricted Embryo_S294_6_1B
TS22: retina Strong Regionally restricted Embryo_S294_6_1B
TS22: lens Absent
TS22: cornea Absent
TS22: optic nerve Absent
TS22: nose Strong Regionally restricted Embryo_S294_6_5B
TS22: olfactory epithelium Strong Regionally restricted Embryo_S294_6_5B
TS22: ear Strong Regionally restricted Embryo_S294_6_1A
TS22: inner ear Weak Regionally restricted Embryo_S294_6_2B
TS22: cochlea Absent
TS22: inner ear labyrinth Weak Regionally restricted Embryo_S294_6_2B
TS22: middle ear Strong Ubiquitous Embryo_S294_6_1A
TS22: alimentary system Strong Regionally restricted Embryo_S294_6_3B Expression was strong in the digestive system.
TS22: intestine Strong Regionally restricted Embryo_S294_6_5A
TS22: salivary gland Strong Regionally restricted Embryo_S294_6_2D
TS22: tongue Strong Regionally restricted Embryo_S294_6_3D
TS22: tooth Strong Regionally restricted Embryo_S294_6_3C
TS22: palatal shelf Strong Regionally restricted Embryo_S294_6_3C
TS22: esophagus Strong Regionally restricted Embryo_S294_6_3B
TS22: stomach Strong Regionally restricted Embryo_S294_6_1C
TS22: liver Strong Ubiquitous Embryo_S294_6_1A
TS22: respiratory system Strong Regionally restricted Embryo_S294_6_2A
TS22: pharynx Strong Regionally restricted Embryo_S294_6_3C
TS22: larynx Strong Regionally restricted Embryo_S294_6_3C
TS22: trachea Moderate Ubiquitous Embryo_S294_6_3D
TS22: main bronchus Absent
TS22: lung Strong Regionally restricted Embryo_S294_6_2A
TS22: urinary system Strong Regionally restricted Embryo_S294_6_2B Expression was strong in the genito-urinary system.
TS22: metanephros Strong Regionally restricted Embryo_S294_6_2D
TS22: ureter Absent
TS22: bladder Weak Regionally restricted Embryo_S294_6_4C
TS22: urethra Moderate Regionally restricted Embryo_S294_6_4C
TS22: reproductive system Strong Regionally restricted Embryo_S294_6_5B
TS22: genital tubercle Strong Regionally restricted Embryo_S294_6_5B
TS22: gonad Absent
TS22: gland Strong Regionally restricted Embryo_S294_6_3A Expression was strong in the endocrine system.
TS22: thyroid gland Moderate Regionally restricted Embryo_S294_6_3A
TS22: pituitary gland Moderate Regionally restricted Embryo_S294_6_3A
TS22: pancreas Strong Regionally restricted Embryo_S294_6_3A
TS22: adrenal gland Absent
TS22: cardiovascular system Absent
TS22: heart Absent
TS22: heart atrium Absent
TS22: heart ventricle Absent
TS22: blood vessel Absent
TS22: hemolymphoid system Strong Regionally restricted Embryo_S294_6_3A Expression was strong in the immune system.
TS22: spleen primordium Absent
TS22: thymus primordium Strong Ubiquitous Embryo_S294_6_3A
TS22: appendicular skeleton Absent Expression was not detected in the skeleton (limbs, shoulder, hip).
TS22: musculature Weak Ubiquitous Embryo_S294_6_1B
TS22: face Absent Expression was not detected in the face/soft tissues.
TS22: facial bone primordium Strong Regionally restricted Embryo_S294_6_3D
TS22: cranium Strong Regionally restricted Embryo_S294_6_2B Expression was strong in the skull (base and vault).
TS22: axial skeleton Absent
TS22: tail Moderate Regionally restricted Embryo_S294_6_5B
TS22: forelimb Moderate Regionally restricted Embryo_S294_6_1A
TS22: hindlimb Moderate Regionally restricted Embryo_S294_6_2B
TS22: integumental system Strong Regionally restricted Embryo_S294_6_2A
TS22: skin Strong Ubiquitous Embryo_S294_6_1A
TS22: hair Strong Regionally restricted Embryo_S294_6_2A
TS22: vibrissa follicle Strong Regionally restricted Embryo_S294_6_2A Expression was strong in whisker follicle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory