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Gene Expression Data
Assay Details
Assay
Reference: J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
Assay type: RNA in situ
MGI Accession ID: MGI:5422464
Gene symbol: Map2k4
Gene name: mitogen-activated protein kinase kinase 4
Probe: T50670
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Cryosections of fresh frozen material were fixed in 4% paraformaldehyde for 20 min. before further processing. A tyramide-biotin/streptavidin amplification step was included in the in situ hybridization procedure. These data were downloaded from GenePaint.org on 1/30/12.
Results
Specimen MH1780; Specimen C1850: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nervous system Strong Regionally restricted Embryo_C1850_3_5A
TS22: central nervous system Strong Regionally restricted Embryo_C1850_3_5A
TS22: telencephalon Moderate Regionally restricted Embryo_C1850_3_5D
TS22: cerebral cortex Moderate Regionally restricted Embryo_C1850_3_5D
TS22: neocortex Weak Regionally restricted Embryo_C1850_3_6B
TS22: olfactory cortex Moderate Regionally restricted Embryo_C1850_3_5D
TS22: main olfactory bulb Moderate Regionally restricted Embryo_C1850_3_5D
TS22: piriform cortex Weak Regionally restricted Embryo_C1850_3_6B
TS22: hippocampus Weak Regionally restricted Embryo_C1850_3_5B
TS22: basal ganglia Weak Regionally restricted Embryo_C1850_3_5D
TS22: corpus striatum Absent Expression was not detected in the corpus striatum (lateral ganglionic eminence).
TS22: basal forebrain Weak Regionally restricted Embryo_C1850_3_6A
TS22: amygdala Weak Regionally restricted Embryo_C1850_3_5D
TS22: telencephalon septum Absent
TS22: pallidum Absent Expression was not detected in the pallidum (medial ganglionic eminence).
TS22: diencephalon Moderate Regionally restricted Embryo_C1850_3_3D
TS22: thalamus Moderate Regionally restricted Embryo_C1850_3_3D
TS22: hypothalamus Weak Regionally restricted Embryo_C1850_3_3D
TS22: midbrain Moderate Regionally restricted Embryo_C1850_3_3D
TS22: pretectum Weak Regionally restricted Embryo_C1850_3_3B
TS22: superior colliculus Weak Regionally restricted Embryo_C1850_3_3B
TS22: inferior colliculus Weak Regionally restricted Embryo_C1850_3_3B
TS22: midbrain tegmentum Moderate Regionally restricted Embryo_C1850_3_3D
TS22: hindbrain Moderate Regionally restricted Embryo_C1850_3_2C
TS22: cerebellum Weak Regionally restricted Embryo_C1850_3_2C
TS22: pons Moderate Regionally restricted Embryo_C1850_3_2C
TS22: medulla oblongata Moderate Regionally restricted Embryo_C1850_3_2C
TS22: spinal cord Strong Regionally restricted Embryo_C1850_3_5A
TS22: choroid plexus Absent
TS22: meninges Weak Regionally restricted Embryo_C1850_3_1B
TS22: peripheral nervous system Strong Regionally restricted Embryo_C1850_3_5A
TS22: cranial ganglion Strong Regionally restricted Embryo_C1850_3_5A
TS22: dorsal root ganglion Moderate Regionally restricted Embryo_C1850_3_5B
TS22: eye Weak Regionally restricted Embryo_C1850_3_1A
TS22: retina Weak Regionally restricted Embryo_C1850_3_1A
TS22: lens Weak Regionally restricted Embryo_C1850_3_1A
TS22: cornea Absent
TS22: optic nerve Absent
TS22: nose Weak Regionally restricted Embryo_C1850_3_4A
TS22: olfactory epithelium Weak Regionally restricted Embryo_C1850_3_4A
TS22: ear Weak Regionally restricted Embryo_C1850_3_5B
TS22: inner ear Weak Regionally restricted Embryo_C1850_3_4D
TS22: cochlea Weak Regionally restricted Embryo_C1850_3_5B
TS22: inner ear labyrinth Absent
TS22: middle ear Absent
TS22: alimentary system Weak Regionally restricted Embryo_C1850_3_3B Expression was weak in the digestive system.
TS22: intestine Weak Regionally restricted Embryo_C1850_3_4B
TS22: salivary gland Weak Regionally restricted Embryo_C1850_3_2C
TS22: tongue Weak Regionally restricted Embryo_C1850_3_4C
TS22: tooth Weak Regionally restricted Embryo_C1850_3_3B
TS22: palatal shelf Absent
TS22: esophagus Weak Regionally restricted Embryo_C1850_3_3C
TS22: stomach Weak Regionally restricted Embryo_C1850_3_3B
TS22: liver Absent
TS22: respiratory system Weak Regionally restricted Embryo_C1850_3_3C
TS22: pharynx Weak Regionally restricted Embryo_C1850_3_3C
TS22: larynx Weak Regionally restricted Embryo_C1850_3_3C
TS22: trachea Weak Regionally restricted Embryo_C1850_3_3C
TS22: main bronchus Absent
TS22: lung Weak Regionally restricted Embryo_C1850_3_4C
TS22: urinary system Weak Regionally restricted Embryo_C1850_3_5A Expression was weak in the genito-urinary system.
TS22: metanephros Weak Regionally restricted Embryo_C1850_3_3B
TS22: ureter Absent
TS22: bladder Weak Regionally restricted Embryo_C1850_3_5A
TS22: urethra Weak Regionally restricted Embryo_C1850_3_5A
TS22: reproductive system Weak Regionally restricted Embryo_C1850_3_5A
TS22: genital tubercle Weak Regionally restricted Embryo_C1850_3_5A
TS22: gonad Weak Regionally restricted Embryo_C1850_3_5A
TS22: gland Weak Regionally restricted Embryo_C1850_3_4A Expression was weak in the endocrine system.
TS22: thyroid gland Weak Scattered Embryo_C1850_3_4B
TS22: pituitary gland Weak Regionally restricted Embryo_C1850_3_4A
TS22: pancreas Weak Regionally restricted Embryo_C1850_3_3C
TS22: adrenal gland Absent
TS22: cardiovascular system Absent
TS22: heart Absent
TS22: heart atrium Absent
TS22: heart ventricle Absent
TS22: blood vessel Absent
TS22: hemolymphoid system Weak Regionally restricted Embryo_C1850_3_4B Expression was weak in the immune system.
TS22: spleen primordium Absent
TS22: thymus primordium Weak Scattered Embryo_C1850_3_4B
TS22: appendicular skeleton Absent Expression was not detected in the skeleton (limbs, shoulder, hip).
TS22: musculature Absent
TS22: face Absent Expression was not detected in the face/soft tissues.
TS22: facial bone primordium Absent
TS22: cranium Absent Expression was not detected in the skull (base and vault).
TS22: axial skeleton Weak Regionally restricted Embryo_C1850_3_5A
TS22: tail Weak Regionally restricted Embryo_C1850_3_5A
TS22: forelimb Weak Regionally restricted Embryo_C1850_3_1A
TS22: hindlimb Weak Regionally restricted Embryo_C1850_3_2A
TS22: integumental system Weak Regionally restricted Embryo_C1850_3_6D
TS22: skin Weak Regionally restricted Embryo_C1850_3_5D
TS22: hair Weak Regionally restricted Embryo_C1850_3_6D
TS22: vibrissa follicle Weak Regionally restricted Embryo_C1850_3_6D Expression was weak in whisker follicle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory