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Gene Expression Data
Assay Details
Assay
Reference: J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
Assay type: RNA in situ
MGI Accession ID: MGI:5421095
Gene symbol: Bub1
Gene name: BUB1, mitotic checkpoint serine/threonine kinase
Probe: MH542 probe 405
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Cryosections of fresh frozen material were fixed in 4% paraformaldehyde for 20 min. before further processing. A tyramide-biotin/streptavidin amplification step was included in the in situ hybridization procedure. These data were downloaded from GenePaint.org on 1/30/12.
Results
Specimen MH542; Specimen C1345: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nervous system Strong Regionally restricted Embryo_C1345_5_3B
TS22: central nervous system Strong Regionally restricted Embryo_C1345_5_3B
TS22: telencephalon Strong Regionally restricted Embryo_C1345_5_3B
TS22: cerebral cortex Strong Regionally restricted Embryo_C1345_5_4C
TS22: neocortex Strong Regionally restricted Embryo_C1345_5_2B
TS22: olfactory cortex Moderate Regionally restricted Embryo_C1345_5_4C
TS22: main olfactory bulb Moderate Regionally restricted Embryo_C1345_5_4C
TS22: piriform cortex Absent
TS22: hippocampus Strong Regionally restricted Embryo_C1345_5_4C
TS22: basal ganglia Strong Regionally restricted Embryo_C1345_5_3B
TS22: corpus striatum Strong Regionally restricted Embryo_C1345_5_2B Expression was strong in the corpus striatum (lateral ganglionic eminence).
TS22: basal forebrain Strong Regionally restricted Embryo_C1345_5_3B
TS22: amygdala Absent
TS22: telencephalon septum Absent
TS22: pallidum Strong Regionally restricted Embryo_C1345_5_3B Expression was strong in the pallidum (medial ganglionic eminence).
TS22: diencephalon Moderate Regionally restricted Embryo_C1345_5_3D
TS22: thalamus Moderate Regionally restricted Embryo_C1345_5_3D
TS22: hypothalamus Moderate Regionally restricted Embryo_C1345_5_4C
TS22: midbrain Strong Regionally restricted Embryo_C1345_5_4C
TS22: pretectum Absent
TS22: superior colliculus Moderate Regionally restricted Embryo_C1345_5_4C
TS22: inferior colliculus Strong Regionally restricted Embryo_C1345_5_4C
TS22: midbrain tegmentum Weak Regionally restricted Embryo_C1345_5_3C
TS22: hindbrain Moderate Regionally restricted Embryo_C1345_5_5A
TS22: cerebellum Weak Regionally restricted Embryo_C1345_5_4B
TS22: pons Weak Regionally restricted Embryo_C1345_5_3C
TS22: medulla oblongata Weak Regionally restricted Embryo_C1345_5_5A
TS22: spinal cord Strong Regionally restricted Embryo_C1345_5_4B
TS22: choroid plexus Absent
TS22: meninges Absent
TS22: peripheral nervous system Absent
TS22: cranial ganglion Absent
TS22: dorsal root ganglion Absent
TS22: eye Moderate Regionally restricted Embryo_C1345_5_1A
TS22: retina Moderate Regionally restricted Embryo_C1345_5_1A
TS22: lens Absent
TS22: optic nerve Moderate Regionally restricted Embryo_C1345_5_2B
TS22: nose Moderate Regionally restricted Embryo_C1345_5_3A
TS22: olfactory epithelium Moderate Regionally restricted Embryo_C1345_5_3A
TS22: ear Moderate Regionally restricted Embryo_C1345_5_5A
TS22: inner ear Moderate Regionally restricted Embryo_C1345_5_5A
TS22: cochlea Moderate Regionally restricted Embryo_C1345_5_5A
TS22: inner ear labyrinth Weak Regionally restricted Embryo_C1345_5_5C
TS22: middle ear Moderate Regionally restricted Embryo_C1345_5_1A
TS22: alimentary system Strong Regionally restricted Embryo_C1345_5_5C Expression was strong in the digestive system.
TS22: intestine Weak Regionally restricted Embryo_C1345_5_4D
TS22: salivary gland Strong Regionally restricted Embryo_C1345_5_5C
TS22: tongue Weak Regionally restricted Embryo_C1345_5_4D
TS22: tooth Strong Regionally restricted Embryo_C1345_5_4D
TS22: palatal shelf Weak Regionally restricted Embryo_C1345_5_4C
TS22: esophagus Moderate Regionally restricted Embryo_C1345_5_4B
TS22: stomach Weak Regionally restricted Embryo_C1345_5_6B
TS22: liver Weak Regionally restricted Embryo_C1345_5_4D
TS22: respiratory system Moderate Regionally restricted Embryo_C1345_5_4B
TS22: pharynx Moderate Regionally restricted Embryo_C1345_5_4B
TS22: larynx Moderate Regionally restricted Embryo_C1345_5_4B
TS22: trachea Moderate Regionally restricted Embryo_C1345_5_4A
TS22: main bronchus Weak Regionally restricted Embryo_C1345_5_4D
TS22: lung Moderate Regionally restricted Embryo_C1345_5_4A
TS22: urinary system Strong Regionally restricted Embryo_C1345_5_6D Expression was strong in the genito-urinary system.
TS22: metanephros Strong Regionally restricted Embryo_C1345_5_5C
TS22: ureter Absent
TS22: bladder Moderate Regionally restricted Embryo_C1345_5_4A
TS22: urethra Weak Regionally restricted Embryo_C1345_5_3D
TS22: reproductive system Strong Regionally restricted Embryo_C1345_5_6D
TS22: genital tubercle Strong Regionally restricted Embryo_C1345_5_3A
TS22: gonad Strong Regionally restricted Embryo_C1345_5_6D
TS22: gland Strong Regionally restricted Embryo_C1345_5_3C Expression was strong in the endocrine system.
TS22: thyroid gland Strong Regionally restricted Embryo_C1345_5_3C
TS22: pituitary gland Moderate Regionally restricted Embryo_C1345_5_4B
TS22: pancreas Weak Regionally restricted Embryo_C1345_5_5C
TS22: adrenal gland Weak Regionally restricted Embryo_C1345_5_6B
TS22: cardiovascular system Weak Regionally restricted Embryo_C1345_5_2D
TS22: heart Weak Regionally restricted Embryo_C1345_5_2D
TS22: heart atrium Weak Regionally restricted Embryo_C1345_5_2D
TS22: heart ventricle Weak Regionally restricted Embryo_C1345_5_3C
TS22: blood vessel Weak Regionally restricted Embryo_C1345_5_4D
TS22: hemolymphoid system Moderate Regionally restricted Embryo_C1345_5_4C Expression was detected in the immune system.
TS22: spleen primordium Absent
TS22: thymus primordium Moderate Ubiquitous Embryo_C1345_5_4C
TS22: appendicular skeleton Absent Expression was not detected in the skeleton (limbs, shoulder, hip).
TS22: musculature Weak Regionally restricted Embryo_C1345_5_6A
TS22: face Strong Regionally restricted Embryo_C1345_5_2B Expression was strong in the face/soft tissues.
TS22: facial bone primordium Absent
TS22: cranium Absent Expression was not detected in the skull (base and vault).
TS22: axial skeleton Absent
TS22: tail Strong Regionally restricted Embryo_C1345_5_3A
TS22: forelimb Strong Regionally restricted Embryo_C1345_5_1B
TS22: hindlimb Strong Regionally restricted Embryo_C1345_5_1B
TS22: integumental system Strong Regionally restricted Embryo_C1345_5_1D
TS22: skin Moderate Regionally restricted Embryo_C1345_5_3A
TS22: hair Strong Regionally restricted Embryo_C1345_5_1D
TS22: vibrissa follicle Strong Regionally restricted Embryo_C1345_5_1D Expression was strong in whisker follicle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory