Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Bpnt1tm2.1Yrk
Name:	3'(2'), 5'-bisphosphate nucleotidase 1; targeted mutation 2.1, John D York
MGI ID:	MGI:5320431
Gene:	Bpnt1  Location: Chr1:185064346-185089974 bp, + strand  Genetic Position: Chr1, 89.49 cM, cytoband H4
Alliance:	Bpnt1tm2.1Yrk page

Germline Transmission:	Earliest citation of germline transmission: J:259846
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was introduced to intron 3 and FRT-neomycin-FRT-loxP sequences were added to intron 5 of the targeted gene. Flp-mediated recombination removed the neo cassette. (J:259846)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Bpnt1 Mutation:	40 strains or lines available

Original:	J:259846 Hudson BH, et al., Modulation of intestinal sulfur assimilation metabolism regulates iron homeostasis. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3000-3005
All:	3 reference(s)