Tg(CD19-BTK)1Rwhe
Transgene Detail
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| Symbol: |
Tg(CD19-BTK)1Rwhe |
| Name: |
transgene insertion 1, Rudolf Hendriks |
| MGI ID: |
MGI:3709187 |
| Synonyms: |
CD19-hBtk |
| Transgene: |
Tg(CD19-BTK)1Rwhe Location: unknown
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| Alliance: |
Tg(CD19-BTK)1Rwhe page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CD19-BTK)1Rwhe expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
BTK (695) |
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Mutation details: A composite fragment composed of 400bp from exons 1-3 of a BTK cDNA as well as 27kb genomic fragment containing exons 3-19 of BTK was placed under the control of the promoter region of human CD19.
(J:120990)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:120990 Maas A, et al., Early arrest in B cell development in transgenic mice that express the E41K Bruton's tyrosine kinase mutant under the control of the CD19 promoter region. J Immunol. 1999 Jun 1;162(11):6526-33 |
| All: |
7 reference(s) |
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Analysis Tools
