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Mtss1tm1Pla
Targeted Allele Detail
Summary
Symbol: Mtss1tm1Pla
Name: MTSS I-BAR domain containing 1; targeted mutation 1, Pekka Lappalainen
MGI ID: MGI:5319219
Gene: Mtss1  Location: Chr15:58813083-58953854 bp, - strand  Genetic Position: Chr15, 25.09 cM
Alliance: Mtss1tm1Pla page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:182970
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA transposon-based method was used to insert a neo cassette into exon 1. Western bot analysis confirmed the absence of protein expression. (J:182970)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 17 assay results
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mtss1 Mutation:  119 strains or lines available
References
Original:  J:182970 Saarikangas J, et al., Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia. J Cell Sci. 2011 Apr 15;124(Pt 8):1245-55
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory