Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(tetO-SMN2,-luc)#bAhmb
Name:	transgene insertion, Arthur H M Burghes
MGI ID:	MGI:5318802
Transgene:	Tg(tetO-SMN2,-luc)#bAhmb  Location: unknown
Alliance:	Tg(tetO-SMN2,-luc)#bAhmb page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence, Reporter) Inducer:    doxycycline/tetracycline Mutation:    Insertion   Tg(tetO-SMN2,-luc)#bAhmb expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human SMN2 (6607) Smn1  (MGI:109257)   Mutation details: The tetracycline response element with two minimal CMV promoters drives inducible expression of human SMN (exons 1 through 8) and a luciferase gene. (J:174960)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available

Original:	J:174960 Le TT, et al., Temporal requirement for high SMN expression in SMA mice. Hum Mol Genet. 2011 Sep 15;20(18):3578-91
All:	1 reference(s)