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Tg(Prox1-tdTomato)12Nrud
Transgene Detail
Summary
Symbol: Tg(Prox1-tdTomato)12Nrud
Name: transgene insertion 12, Nancy H Ruddle
MGI ID: MGI:5316745
Synonyms: ProxTom
Transgene: Tg(Prox1-tdTomato)12Nrud  Location: unknown  
Alliance: Tg(Prox1-tdTomato)12Nrud page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA bacterial artificial chromosome (BAC), RPCI23-385H16, was used to isolate 144kb sequence containing the entire mouse Prox1 (prospero-related homeobox 1) gene. A 144kb portion of this BAC, containing only Prox1, was modified to include a red fluorescent protein, tdTomato, from the pClasper vector, between amino acid 5 and the Prox1 nuclear localization sequence. Line 12 contains 10 copies of the transgene. (J:182015)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:182015 Truman LA, et al., ProxTom Lymphatic Vessel Reporter Mice Reveal Prox1 Expression in the Adrenal Medulla, Megakaryocytes, and Platelets. Am J Pathol. 2012 Apr;180(4):1715-25
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory