Tg(Slc17a6-COP4*H134R/EYFP)2Oki
Transgene Detail
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| Symbol: |
Tg(Slc17a6-COP4*H134R/EYFP)2Oki |
| Name: |
transgene insertion 2, Ole Kiehn |
| MGI ID: |
MGI:5314662 |
| Synonyms: |
Vglut2-ChR2-YFP, vGluT2-YFP |
| Transgene: |
Tg(Slc17a6-COP4*H134R/EYFP)2Oki Location: unknown
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| Alliance: |
Tg(Slc17a6-COP4*H134R/EYFP)2Oki page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: A bacterial articificial chromosone (BAC) # RPCI23-84M15 containing the mouse Vglut2 gene was modified by the introduction of a human codon-optimized channel rhodopsin (hChR2) and a gain-of-function H134R substitution fused to an enhanced yellow fluorescent protein sequence (EYFP) and inserted to inactivate the Vglut2 gene. Line 2 was generated.
(J:180947)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:180947 Hagglund M, et al., Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion. Nat Neurosci. 2010 Feb;13(2):246-52 |
| All: |
8 reference(s) |
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Analysis Tools
