Tg(Th-FTH1)1Jkan
Transgene Detail
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| Symbol: |
Tg(Th-FTH1)1Jkan |
| Name: |
transgene insertion 1, Julie Andersen |
| MGI ID: |
MGI:5314634 |
| Transgene: |
Tg(Th-FTH1)1Jkan Location: unknown
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| Alliance: |
Tg(Th-FTH1)1Jkan page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Th-FTH1)1Jkan expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
FTH1 (2495) |
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Tg(Th-FTH1)1Jkan expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| rat |
Th (25085) |
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Mutation details: The transgene construct contained a 2.6kb fragment of the human FTH1 (ferritin, heavy polypeptide 1) gene lacking the iron-response element (IRE) under the control of the rat Th (tyrosine hydroxylase) promoter, and SV40 polyA signal Line 1 was generated.
(J:139481)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:139481 Kaur D, et al., Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease. Neuron. 2003 Mar 27;37(6):899-909 |
| All: |
1 reference(s) |
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Analysis Tools
