Gene Expression Data
Assay Details
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Assay
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Reference:
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J:179032
Sharlin DS, et al., Developmental and cell-specific expression of thyroid hormone transporters in the mouse cochlea. Endocrinology. 2011 Dec;152(12):5053-64
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5311389
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Gene symbol:
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Slco1c1
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Gene name:
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solute carrier organic anion transporter family, member 1c1
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Antibody:
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anti-Oatp1c1
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Detection system:
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Secondary antibody coupled to Alexa Fluor
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Assay notes:
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The specimens used in this assay were post-fixed with methanol.
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Results
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Specimen
5B:
postnatal day 10
(more  )
Specimen
5B:
(close  )
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Genetic Background:
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C57BL/6J
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlear duct |
Present |
Regionally restricted |
5B
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Signal was detected in the cell membrane of the tympanic border cells.
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| TS28: osseus spiral lamina |
Present |
Regionally restricted |
5B
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Signal was detected in fibrocytes at the tympanic lip of the osseous spiral lamina.
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Specimen
5C:
postnatal day 7
(more )
Note: Double labeled: green - Slco1c1; red - Tubb3 (assay MGI:5311384).
Specimen
5C:
(close )
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Genetic Background:
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C57BL/6J
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Age:
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postnatal day 7
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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Note:
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Double labeled: green - Slco1c1; red - Tubb3 (assay MGI:5311384).
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Specimen
5D:
postnatal day 10
(more )
Note: Double labeled: green - Slco1c1; red - Pecam1 (assay MGI:5311190).
Specimen
5D:
(close )
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Genetic Background:
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C57BL/6J
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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Note:
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Double labeled: green - Slco1c1; red - Pecam1 (assay MGI:5311190).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: spiral ligament |
Present |
Regionally restricted |
5D
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Signal was detected in fibrocytes in the spiral ligament.
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| TS28: cochlear duct |
Present |
Regionally restricted |
5D
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Signal was detected in tympanic border cells.
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| TS28: blood vessel |
Absent |
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5D
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Does not co-stain with CD31-positive vessels in the spiral ligament.
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Specimen
5F:
postnatal day 10
(more )
Note: Double labeled: green - Slco1c1; red - Pecam1 (assay MGI:5311190).
Specimen
5F:
(close )
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Genetic Background:
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C57BL/6J
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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Note:
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Double labeled: green - Slco1c1; red - Pecam1 (assay MGI:5311190).
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Specimen
5H:
postnatal day 10
(more )
Note: Double labeled: green - Slco1c1; red - Pecam1 (assay MGI:5311190).
Specimen
5H:
(close )
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Genetic Background:
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C57BL/6J
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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Note:
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Double labeled: green - Slco1c1; red - Pecam1 (assay MGI:5311190).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: blood vessel |
Present |
Regionally restricted |
5H
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Signal colocalized with CD31 in vessel-like structures in the cochlear nerve.
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Specimen
not shown:
postnatal day 10
(more )
Specimen
not shown:
(close )
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Genetic Background:
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C57BL/6J
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: spiral vessel |
Absent |
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Signal did not colocalize with CD31 in the spiral vessel.
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Specimen
S1D Oatp1c1+/+ top:
postnatal day 15
(more )
Specimen
S1D Oatp1c1<+/+> top:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 15
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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Specimen
S1D Oatp1c1+/+ bottom:
postnatal day 15
(more )
Specimen
S1D Oatp1c1<+/+> bottom:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 15
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlear duct |
Present |
Regionally restricted |
S1D Oatp1c1+/+ bottom
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Signal was detected in the tympanic border cells.
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Specimen
S1D Oatp1c1<-/-> top:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Slco1c1tm1.1Arte/Slco1c1tm1.1Arte
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Age:
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postnatal day 15
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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Specimen
S1D Oatp1c1<-/-> bottom:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Slco1c1tm1.1Arte/Slco1c1tm1.1Arte
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Age:
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postnatal day 15
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlear duct |
Absent |
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S1D Oatp1c1-/- bottom
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Signal was not detected in the tympanic border cells.
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Specimen
not shown:
postnatal day 7
(more )
Specimen
not shown:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 7
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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Specimen
not shown:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Slco1c1tm1.1Arte/Slco1c1tm1.1Arte
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Age:
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postnatal day 7
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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