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Gene Expression Data
Assay Details
Assay
Reference: J:179032 Sharlin DS, et al., Developmental and cell-specific expression of thyroid hormone transporters in the mouse cochlea. Endocrinology. 2011 Dec;152(12):5053-64
Assay type: RNA in situ
MGI Accession ID: MGI:5310940
Gene symbol: Slco1c1
Gene name: solute carrier organic anion transporter family, member 1c1
Probe: Oatp1c1 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1D E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cochlea Absent 1D E18
Specimen 1D P3: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cochlear duct Weak Regionally restricted 1D P3 Signal was weakly detected in the tympanic border cells.
TS27: spiral ligament Weak Regionally restricted 1D P3 Signal was weakly detected in fibrocytes in the spiral ligament.
Specimen 1D P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: spiral ligament Present Regionally restricted 1D P5 Signal was detected in lower regions of spiral ligament.
TS28: spiral limbus Present Regionally restricted 1D P5 Signal was detected in fibrocytes in the spiral limbus.
TS28: modiolus Present 1D P5
TS28: osseus spiral lamina Present 1D P5
Specimen 1D P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: spiral ligament Present Widespread 1D P7
TS28: spiral limbus Present 1D P7
TS28: cochlear duct Present Regionally restricted 1D P7 Signal increased substantially in the tympanic border cells.
TS28: modiolus Present 1D P7
TS28: osseus spiral lamina Present 1D P7
Specimen 1D P10: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: spiral ligament Present Widespread 1D P10
TS28: spiral limbus Present Regionally restricted 1D P10 Signal was detected in fibrocytes in the spiral limbus.
TS28: cochlear duct Present Regionally restricted 1D P10 Signal increased substantially in the tympanic border cells.
TS28: modiolus Present 1D P10
TS28: osseus spiral lamina Present 1D P10
Specimen not shown: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: spiral ligament Present Widespread
TS28: spiral limbus Present Signal was detected in fibrocytes in the spiral limbus.
TS28: modiolus Present
TS28: osseus spiral lamina Present
TS28: cochlear duct Present Regionally restricted Signal in the tympanic border cells increased substantially between P7 and P15
Specimen 5A: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cochlear duct Strong Regionally restricted 5A Signal was detected in the tympanic border cells.
TS28: osseus spiral lamina Strong Regionally restricted 5A Signal was detected in fibrocytes at the tympanic lip.
Specimen 5E: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: spiral ligament Present 5E
TS28: stria vascularis Absent 5E
Specimen 5G: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: blood vessel Present Regionally restricted 5G Signal was detected in vessel-like structures in the cochlear nerve.
Specimen 6D Tshr+/+: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cochlea Present 6D +/+
Specimen 6D Tshr-/-: postnatal day 7; Tshrtm1Rmar/Tshrtm1Rmar (more )
Structure Level Pattern Image Note
TS28: cochlea Present 6D Tshr-/- The expression was reduced in mutant cochlea, consistent with a delay in tissue development.
Specimen S1 Oatp1c1: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cochlea Present S1A Oatp1c1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory