Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Akap13tm1Segj
Name:	A kinase anchor protein 13; targeted mutation 1, James H Segars
MGI ID:	MGI:5308769
Synonyms:	brx-
Gene:	Akap13  Location: Chr7:75105282-75404357 bp, + strand  Genetic Position: Chr7, 43.76 cM, cytoband D1
Alliance:	Akap13tm1Segj page

Germline Transmission:	Earliest citation of germline transmission: J:111574
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neo cassette replaced exon 5, which encodes the Dbl homology (DH) domain. RT-PCR confirmed the absence of transcript expression in embryos. (J:181088)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	24 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Akap13 Mutation:	178 strains or lines available

Original:	J:111574 Kino T, et al., Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system. J Biol Chem. 2006 Apr 7;281(14):9118-26
All:	5 reference(s)