Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Fabp2-CFTR*)1Wsh
Name:	transgene insertion 1, Michael J Welsh
MGI ID:	MGI:5308021
Synonyms:	CFTRdeltaR
Transgene:	Tg(Fabp2-CFTR*)1Wsh  Location: unknown
Alliance:	Tg(Fabp2-CFTR*)1Wsh page

Strain of Origin:

(C57BL/6 x SJL/J)F1

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(Fabp2-CFTR*)1Wsh expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human CFTR (1080) Cftr  (MGI:88388)   Mutation details: Nucleotides -1178 to +28 of the rat intestinal fatty acid binding protein (Fabp2) promoter drive expression of a human CFTR cDNA from which sequences encoding N-terminal residues 708-759 have been deleted. Line 1 was generated. (J:169220)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:169220 Ostedgaard LS, et al., Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR-/- mice. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2921-6
All:	1 reference(s)