Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Grin2ctm2(icre)Mwa
Name:	glutamate receptor, ionotropic, NMDA2C (epsilon 3); targeted mutation 2, Masahiko Watanabe
MGI ID:	MGI:5306941
Synonyms:	E3CreN, GluN2CiCre
Gene:	Grin2c  Location: Chr11:115139995-115158069 bp, - strand  Genetic Position: Chr11, 80.8 cM
Alliance:	Grin2ctm2(icre)Mwa page

Germline Transmission:	Earliest citation of germline transmission: J:180582
Parent Cell Line:	RENKA (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Grin2ctm2(icre)Mwa expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Grin2c (MGI:95822)   Mutation details: A vector was constructed to insert an improved cre recombinase and an Frt-flanked neomycin cassette into the translation initiation site (in-frame) of the Grin2c gene by homologous recombination in RENKA ES cells. (J:180582)

Activity:	Tissue activity of this recombinase allele
Driver:	Grin2c (mouse) Summary of all recombinase alleles driven by Grin2c. Alliance mouse Grin2c gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grin2c Mutation:	56 strains or lines available

Original:	J:180582 Miyazaki T, et al., Cav2.1 in Cerebellar Purkinje Cells Regulates Competitive Excitatory Synaptic Wiring, Cell Survival, and Cerebellar Biochemical Compartmentalization. J Neurosci. 2012 Jan 25;32(4):1311-1328
All:	8 reference(s)