Tg(CRKL*)8746Hkp Transgene Detail MGI Mouse (MGI:5305978)

Tg(CRKL*)8746Hkp
Transgene Detail

Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Summary

Symbol:	Tg(CRKL*)8746Hkp
Name:	transgene insertion 8746, Nora Heisterkamp
MGI ID:	MGI:5305978
Synonyms:	5xCrkl
Transgene:	Tg(CRKL*)8746Hkp Location: unknown
Alliance:	Tg(CRKL*)8746Hkp page

Transgene
origin

Strain of Origin:

(C57BL/6 x SJL)F2

Transgene
description

Transgene Type:

Transgenic (Humanized sequence, Inserted expressed sequence)

Mutation:

Insertion

Tg(CRKL*)8746Hkp expresses 1 gene

Mutation details: This transgene was generated to contain the promoter-exon 1 of the human v-crk sarcoma virus CT10 oncogene homolog (CRKL) gene, separated by intron sequences from exon 2/3. Line 8746 contains 5 copies of the transgene. (J:68514)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

Original:	J:68514 Hemmeryckx B, et al., Crkl enhances leukemogenesis in BCR/ABL P190 transgenic mice. Cancer Res. 2001 Feb 15;61(4):1398-405
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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