Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gaktm2Legr
Name:	cyclin G associated kinase; targeted mutation 2, Lois E Greene
MGI ID:	MGI:5305733
Synonyms:	GAKfl
Gene:	Gak  Location: Chr5:108717277-108777621 bp, - strand  Genetic Position: Chr5, 53.2 cM
Alliance:	Gaktm2Legr page

Germline Transmission:	Earliest citation of germline transmission: J:180119
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 1. A floxed neo cassette was inserted downstream of exon 1. (J:180119)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gak Mutation:	59 strains or lines available

Original:	J:180119 Lee DW, et al., Essential role of cyclin-G-associated kinase (Auxilin-2) in developing and mature mice. Mol Biol Cell. 2008 Jul;19(7):2766-76
All:	3 reference(s)