Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Acta2-cre/ERT2)#Pcn
Name:	transgene insertion, Pierre Chambon
MGI ID:	MGI:5305721
Synonyms:	alphaSMA-Cre-ERT2, SmaCreER
Transgene:	Tg(Acta2-cre/ERT2)#Pcn  Location: unknown
Alliance:	Tg(Acta2-cre/ERT2)#Pcn page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Acta2-cre/ERT2)#Pcn expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Acta2 (MGI:87909)   Mutation details: A construct containing cre fused to ERT2 followed by an frt flanked PGK-neo cassette was inserted at the initiation codon of Acta2 in a 175 kb mouse BAC. Tamoxifen-induced cre activity was seen in smooth muscle cells. (J:144642)

Activity:	Tissue activity of this recombinase allele
Driver:	Acta2 (mouse) Summary of all recombinase alleles driven by Acta2. Comparative matrix view of recombinase activities Alliance mouse Acta2 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:144642 Wendling O, et al., Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse. Genesis. 2009 Jan;47(1):14-8
All:	60 reference(s)