Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Tn(sb-SBlac)C.176599bFsp
Name:	transposon insertion C.176599b, Francois Spitz
MGI ID:	MGI:5305460
Synonyms:	HoxDTpSB1, SB176599b
Transgene:	Tn(sb-SBlac)C.176599bFsp  Location: unknown  Genetic Position: Chr2, Syntenic
Alliance:	Tn(sb-SBlac)C.176599bFsp page

Strain of Origin:

Not Specified

Allele Type:    Transposon induced (Conditional ready, Reporter) Mutation:    Transposon insertion   Mutation details: Mobilization of the transposon from TgTn(sb-SBlac)CFsp transgenic mice with Sleeping Beauty transposase from an unidentified line of TgTn(sb-SBlac)15Fsp transgenic mice results in the integration of the transposon at chr2:73958058-73958059 (GRCm39) in reverse (tel-cen) orientation. This location is in the gene desert between Atp5g3 and Lnp. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. LacZ expression is detected in the distal limbs and genital bud of E11.5 embryos. (J:180121)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:180121 Ruf S, et al., Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor. Nat Genet. 2011 Apr;43(4):379-86
All:	5 reference(s)