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Gene Expression Data
Assay Details
Assay
Reference: J:50138 Niederreither K, et al., Expression of T:G mismatch-specific thymidine-DNA glycosylase and DNA methyl transferase genes during development and tumorigenesis. Oncogene. 1998 Sep 24;17(12):1577-85
Assay type: RNA in situ
MGI Accession ID: MGI:5304682
Gene symbol: Dnmt1
Gene name: DNA methyltransferase 1
Probe: Dnmt1 cDNA2
Probe preparation: Antisense labelled with radioactivity RNA
Results
Specimen Not shown E7.5: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Present Diffuse The authors state that expression was diffuse until ~E14.5.

Specimen Not shown E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: embryo Present Diffuse The authors state that expression was diffuse until ~E14.5.

Specimen Not shown E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: embryo Present Diffuse The authors state that expression was diffuse until ~E14.5.

Specimen Not shown, E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: embryo Present

Specimen 2C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: intestine Strong 2C
TS26: metanephros Strong 2C
TS26: nasal cavity epithelium Strong 2C
TS26: retina Strong 2C
TS26: thymus Strong 2C
TS26: tooth Strong 2C
TS26: vibrissa Strong 2C

Specimen 4A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: seminiferous cord Strong 4A MTase

Specimen 4B: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule Strong 4B MTase

Specimen 4C: postnatal day 40 (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule Strong 4C MTase Expression varied among different seminiferous tubules of a given testis section which differ in their stage of spermatogenic cycle.

Specimen 4D: postnatal day 40 (more )
Structure Level Pattern Image Note
TS28: ovary growing follicle Strong 4D MTase
TS28: ovary primary follicle Strong 4D MTase
TS28: ovary mature follicle Present Regionally restricted 4D MTase Expression is in the corona radiata.
TS28: corpus luteum Weak 4D MTase

Specimen Not shown, P: postnatal (more )
Structure Level Pattern Image Note
TS28: heart Weak
TS28: liver Weak
TS28: lung Weak
TS28: skin Weak
TS28: thymus Weak

Specimen 5A: postnatal (more )
Structure Level Pattern Image Note
TS28: mammary gland epithelium Weak 5A MTase Expression is in the lactating mammary gland epithelium.

Specimen 6A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: bone Weak 6A MTase


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory