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Gene Expression Data
Assay Details
Assay
Reference: J:91361 Kurpakus MA, et al., Expression of keratins K12, K4 and K14 during development of ocular surface epithelium. Curr Eye Res. 1994 Nov;13(11):805-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5304465
Gene symbol: Krt4
Gene name: keratin 4
Antibody: Clone 6B10
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 2C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Absent 2C

Specimen 2D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: conjunctival sac Present 2D

Specimen 6A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cornea epithelium Absent 6A
TS23: conjunctival sac Present Regionally restricted 6A Expression in a subpopulation of superficial cells of the primitive conjunctival epithelium within the lid bud.
TS23: head Strong Regionally restricted 6A Strong expression in suprabasal cells of the head ectoderm adjacent to the lid bud.

Specimen 6B: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cornea epithelium Present Regionally restricted 6B Expression in some superficial corneal epithelial cells.
TS26: conjunctival sac Present Regionally restricted 6B Expression in suprabasal layers of all three types of conjunctival epithelium.
TS26: epidermis Absent 6B Authors state that expression stops abruptly at the interface of the palpebral conjunctival epithelium with the epidermis of the eyelids.

Specimen Table 1 E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: cornea Absent

Specimen Table 1 E13: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: cornea Absent

Specimen Table 1 E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cornea Absent
TS22: conjunctival sac Present Regionally restricted Expression in the rudimentary lid in a subpopulation of superficial layers of the invaginating column of cells forming the conjunctival epithelium.

Specimen Table 1 E15: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cornea Absent
TS23: conjunctival sac Weak Regionally restricted Authors report sparse expression.

Specimen Table 1 E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cornea Present Regionally restricted Expression in a population of superficial corneal epithelial cells.
TS24: conjunctival sac Present

Specimen Table 1 E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cornea Present Regionally restricted Expression in a population of superficial corneal epithelial cells.
TS26: conjunctival sac Present

Specimen Table 1 E20: embryonic day 20.0 (more )
Structure Level Pattern Image Note
TS26: cornea Present Regionally restricted Expression in a population of superficial corneal epithelial cells.
TS26: conjunctival sac Present

Specimen Table 1 P-N: postnatal (more )
Structure Level Pattern Image Note
TS28: cornea Present Regionally restricted Expression in a population of superficial corneal epithelial cells.
TS28: conjunctival sac Present

Specimen Table 1 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cornea Absent
TS28: conjunctival sac Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory