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Gene Expression Data
Assay Details
Assay
Reference: J:178042 Frojmark AS, et al., Mutations in Frizzled 6 cause isolated autosomal-recessive nail dysplasia. Am J Hum Genet. 2011 Jun 10;88(6):852-60
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5304365
Gene symbol: Fzd6
Gene name: frizzled class receptor 6
Reporter: lacZ
Antibody: anti-B-galactosidase (Abcam)
Results
Specimen 3C E14.5: embryonic day 14.5; Fzd6tm1Nat/Fzd6+ (more )
Structure Level Pattern Image Note
TS22: hindlimb digit Present 3C E14.5

Specimen 3C E15.5: embryonic day 15.5; Fzd6tm1Nat/Fzd6+ (more )
Structure Level Pattern Image Note
TS23: foot epidermis Present Regionally restricted 3C E15.5 Around the digital tip.
TS23: foot dermis Present Regionally restricted 3C E15.5 Expression is in a few foci.

Specimen 3C E16.5: embryonic day 16.5; Fzd6tm1Nat/Fzd6+ (more )
Structure Level Pattern Image Note
TS24: foot epidermis Strong Regionally restricted 3C E16.5 Expression is mainly confined to the epidermis of the digital tips in a region corresponding to the developing nail bed and the ventral part of the digit.
TS24: foot dermis Present Regionally restricted 3C E16.5 Expression is in a few foci.

Specimen 3C E17.5: embryonic day 17.5; Fzd6tm1Nat/Fzd6+ (more )
Structure Level Pattern Image Note
TS25: foot epidermis Present Regionally restricted 3C E17.5 Around the digital tip.
TS25: foot dermis Present Regionally restricted 3C E17.5 Expression is in a few foci.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory