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Gene Expression Data
Assay Details
Assay
Reference: J:80025 Wallis D, et al., The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development. 2003 Jan;130(1):221-32
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5302551
Gene symbol: Gfi1
Gene name: growth factor independent 1 transcription repressor
Antibody: Gfi1 antibody
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: retina Present Regionally restricted 1C Expression is present in cells that are likely to be retinal ganglion cells.

Specimen 1F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: skin Present Single cells 1F Expressing cells are found around the shaft of the whiskers; they are thought to be Merkel cells.

Specimen 1J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lung Present Non-Uniform 1J Expression is present in clusters of cells believed to be neuroepithelial precursor cells.

Specimen 2E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: saccule Present Regionally restricted 2E Expression is present in the developing vestibule organs in positions where the newly developed hair cells are believed to be.
TS22: utricle Present Regionally restricted 2E Expression is present in the developing vestibule organs in positions where the newly developed hair cells are believed to be.

Specimen 2F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: organ of Corti Strong Regionally restricted 2F High levels of expression can be seen in the hair cells.

Specimen 4C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: inner ear vestibular component Present Regionally restricted 4C Expression is present in the otic vesicle.

Specimen 4D: embryonic day 12.5; Atoh1tm2Hzo/Atoh1tm2Hzo (more )
Structure Level Pattern Image Note
TS20: inner ear vestibular component Absent 4D Expression is dramatically reduced or absent in the otic vesicle.

Specimen Not shown: embryonic day 14.5; Atoh1tm2Hzo/Atoh1tm2Hzo (more )
Structure Level Pattern Image Note
TS22: inner ear vestibular component Absent Expression is dramatically reduced or absent in the otic vesicle.

Specimen Not shown: embryonic day 16.5; Atoh1tm2Hzo/Atoh1tm2Hzo (more )
Structure Level Pattern Image Note
TS24: inner ear vestibular component Absent Expression is dramatically reduced or absent in the otic vesicle.

Specimen Not shown: embryonic day 18.5; Atoh1tm2Hzo/Atoh1tm2Hzo (more )
Structure Level Pattern Image Note
TS26: inner ear vestibular component Absent Expression is dramatically reduced or absent in the otic vesicle.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory