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Gt(ROSA)26Sortm1(CAG-GFP/Eif2c2)Zjh
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(CAG-GFP/Eif2c2)Zjh
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Z Josh Huang
MGI ID: MGI:5301865
Synonyms: Gt(ROSA)26Sortm1(CAG-xstpx-GFP/myc/Eif2c2)Zjh
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(CAG-GFP/Eif2c2)Zjh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:179351
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1(CAG-GFP/Eif2c2)Zjh expresses 1 gene
 
Mutation detailsA targeting vector containing loxP site flanked STOP cassette, GFP, and myc-tagged Eif2c2 coding sequence under the control of the CAG promoter was inserted in the Gt(ROSA)26Sor locus. When in the presence of Cre recombinase activity, the GFP/myc tagged Eif2c2 gene is expressed, GFP expression indicates expression of Eif2c2, and the myc epitope tag allowing affinity purification of associated miRNAs. (J:179351)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:179351 He M, et al., Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain. Neuron. 2012 Jan 12;73(1):35-48
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory