Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:177944
Southgate L, et al., Gain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomalies. Am J Hum Genet. 2011 May 13;88(5):574-85
|
Assay type:
|
RNA in situ
|
MGI Accession ID:
|
MGI:5301570
|
Gene symbol:
|
Arhgap31
|
Gene name:
|
Rho GTPase activating protein 31
|
Probe:
|
Arhgap31 probe
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
Visualized with:
|
Alkaline phosphatase
|
|
Results
|
Specimen
2A:
embryonic day 9.5
(more )
Note: This specimen was rendered using optical projection tomography (OPT).
Specimen
2A:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
This specimen was rendered using optical projection tomography (OPT).
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: heart |
Present |
|
2A
|
|
Specimen
2B:
embryonic day 9.5
(more )
Specimen
2B:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2C:
embryonic day 10.5
(more )
Note: This specimen was rendered using optical projection tomography (OPT).
Specimen
2C:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
This specimen was rendered using optical projection tomography (OPT).
|
Specimen
2D:
embryonic day 10.5
(more )
Specimen
2D:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2E:
embryonic day 11.5
(more )
Note: This specimen was rendered using optical projection tomography (OPT).
Specimen
2E:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
This specimen was rendered using optical projection tomography (OPT).
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: surface ectoderm |
Strong |
Regionally restricted |
2E
|
Expression is restricted to distinct regions of the surface ectoderm. Strong expression overlies the entire heart field and symmetrical regions of the head and flank.
|
TS19: footplate ectoderm |
Strong |
|
2E
|
Expression is present in the apical regions.
|
TS19: handplate ectoderm |
Strong |
|
2E
|
Expression is present in the apical regions.
|
Specimen
2F:
embryonic day 11.5
(more )
Specimen
2F:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: surface ectoderm |
Strong |
Regionally restricted |
2F
|
Expression is restricted to distinct regions of the surface ectoderm. Strong expression overlies the entire heart field and symmetrical regions of the head and flank.
|
TS19: footplate ectoderm |
Strong |
|
2F
|
Expression is present in the apical regions.
|
TS19: handplate ectoderm |
Strong |
|
2F
|
Expression is present in the apical regions.
|
Specimen
Not shown:
embryonic day 12.5
(more )
Specimen
Not shown:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
Not Specified
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: epithelium |
Absent |
|
|
There is no expression in the surface ectoderm.
|
|