Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Cpa3-cre)3Glli
Name:	transgene insertion 3, Stephen J Galli
MGI ID:	MGI:5301437
Synonyms:	Cpa3-Cre
Transgene:	Tg(Cpa3-cre)3Glli  Location: unknown
Alliance:	Tg(Cpa3-cre)3Glli page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Cpa3-cre)3Glli expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Cpa3   Mutation details: A 780 bp fragment corresponding to the region immediately 5' to the start codon of the Cpa3 gene was used to drive expression of cre recombinase in the transgene construct. The Cpa3-cre construct was microinjected into C57BL/6-derived embryonic stem (ES) cells. Analysis of mice generated in crosses of cre transgenic to dual reporter (mT/mG) animals showed that most (about 89%) of peritoneal mast cells exhibit high levels of recombination whereas only 13-15% of granulocytes (basophils, eosinophils and neutrophils) display significant recombination. (J:179080)

Activity:	Tissue activity of this recombinase allele
Driver:	Cpa3 (species not specified) Summary of all recombinase alleles driven by Cpa3.

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:179080 Lilla JN, et al., Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice. Blood. 2011 Dec 22;118(26):6930-8
All:	23 reference(s)