Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nos1tm1(cre)Mgmj
Name:	nitric oxide synthase 1, neuronal; targeted mutation 1, Martin G Myers, Jr
MGI ID:	MGI:5301174
Synonyms:	Nos1cre, Nos1-ires-cre
Gene:	Nos1  Location: Chr5:118004904-118096905 bp, + strand  Genetic Position: Chr5, 57.29 cM, cytoband F
Alliance:	Nos1tm1(cre)Mgmj page

Germline Transmission:	Earliest citation of germline transmission: J:179120
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Nos1tm1(cre)Mgmj expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Nos1 (MGI:97360)   Mutation details: An IRES-cre-Frt-neo-Frt cassette was inserted after the stop codon of the final 3' exon of the Nos1 gene by homologous recombination in R1 ES cells. Correctly targeted ES cells were injected into C57BL/6 blastocysts. The resulting chimeric animals were crossed to C57BL/6J mice, and then backcrossed to C57BL/6J for 9 generations. (J:179120, J:183754)

Activity:	Tissue activity of this recombinase allele
Driver:	Nos1 (mouse) Summary of all recombinase alleles driven by Nos1. Alliance mouse Nos1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nos1 Mutation:	82 strains or lines available

Original:	J:179120 Myers MG Jr, Generation of a Nos1-cre knockin allele. MGI Direct Data Submission. 2012;
All:	32 reference(s)