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Gene Expression Data
Assay Details
Assay
Reference: J:168632 Firtina Z, et al., Unfolded Protein Response (UPR) is activated during normal lens development. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):135-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5301161
Gene symbol: Xbp1
Gene name: X-box binding protein 1
Antibody: Anti-XBP-1 (M-186)
Detection system: Secondary antibody
Results
Specimen 3A E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lens vesicle Trace 3A E11.5
Specimen 3A E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present Regionally restricted 3A E12.5 Expression is in primary fiber cells, localized mostly at the apical and basal tips.
TS20: lens vesicle epithelium Weak 3A E12.5
Specimen 3B E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lens fiber Present Regionally restricted 3B E13.5 Expression is throughout lens fiber cell cytoplasm and apical and basal tips.
Specimen 3A E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lens fiber Weak 3B E14.5
TS22: lens epithelium Present 3B E14.5
Specimen 3C, top: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cornea Strong 3C E17.5 top
TS25: lens epithelium Strong 3C E17.5 top
Specimen 3C, bottom: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lens fiber Present Regionally restricted 3C E17.5 bottom Expression is only in peripheral fiber cells.
Specimen 3D, top: postnatal month 3 (more )
Structure Level Pattern Image Note
TS28: lens epithelium Strong 3D 3 mo top
Specimen 3D, bottom: postnatal month 3 (more )
Structure Level Pattern Image Note
TS28: lens fiber Present Regionally restricted 3D 3 mo bottom Expression is in the newly forming lens fiber cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory