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Gene Expression Data
Assay Details
Assay
Reference: J:166449 Nishino J, et al., Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. J Neurosci. 2010 Nov 10;30(45):15228-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5300992
Gene symbol: Egr2
Gene name: early growth response 2
Antibody: PRB-236P
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3F wt: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: sciatic nerve Present 3F wt Krox20
Specimen 3F mut: postnatal day 12; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Structure Level Pattern Image Note
TS28: sciatic nerve Absent 3F mut Krox20 Dramatically reduced expression in Schwann cells relative to wild type.
Specimen S10A +/+ +/+: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: sciatic nerve Present S10A +/+ +/+ Krox20
Specimen S10A LacZ/LacZ +/+: postnatal day 0; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Structure Level Pattern Image Note
TS27: sciatic nerve Absent S10A LacZ/LacZ +/+ Krox20
Specimen S10A +/+ -/-: postnatal day 0; Adam22tm1Sag/Adam22tm1Sag (more )
Structure Level Pattern Image Note
TS27: sciatic nerve Absent S10A +/+ -/- Krox20
Specimen S10A LacZ/LacZ -/-: postnatal day 0; Adam22tm1Sag/Adam22tm1Sag, Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Structure Level Pattern Image Note
TS27: sciatic nerve Absent S10A LacZ/LacZ -/- Krox20
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory