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Gene Expression Data
Assay Details
Assay
Reference: J:166449 Nishino J, et al., Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. J Neurosci. 2010 Nov 10;30(45):15228-40
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5300950
Gene symbol: Lgi4
Gene name: leucine-rich repeat LGI family, member 4
Reporter: lacZ
Antibody: anti-B-galactosidase
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A Glia: postnatal adult; Lgi4tm1Sjm/Lgi4+ (more )
Note: Sections through the gut. Double labeled: green - Lgi4 reporter; red - Fabp7 (BFABP; assay MGI:5300955).
Structure Level Pattern Image Note
TS28: myenteric nerve plexus Present Regionally restricted 2A mut Glia LacZ , 2A mut Glia Merged Expressed in glial cells.
Specimen 2A Neuron: postnatal adult; Lgi4tm1Sjm/Lgi4+ (more )
Note: Sections through the gut. Double labeled: green - Lgi4 reporter; red - Elavl3 (assay MGI:5300958) and Elavl4 (assay MGI:5300960).
Structure Level Pattern Image Note
TS28: myenteric nerve plexus Present Regionally restricted 2A mut Neuron Merged , 2A mut Neuron LacZ Expressed in glial cells, not neurons.
Specimen 2B Glia: postnatal adult; Lgi4tm1Sjm/Lgi4+ (more )
Note: Double labeled: green - Lgi4 reporter; red - Fabp7 (BFABP; assay MGI:5300955).
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present Regionally restricted 2B mut Glia LacZ , 2B mut Glia Merged Expressed in glial cells.
Specimen 2B Neuron: postnatal adult; Lgi4tm1Sjm/Lgi4+ (more )
Note: Double labeled: green - Lgi4 reporter; red - Rbfox3 (assay MGI:5300959).
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present Regionally restricted 2B mut Neuron LacZ , 2B mut Neuron Merged Expressed in glial cells, not neurons.
Specimen 2C Glia: postnatal adult; Lgi4tm1Sjm/Lgi4+ (more )
Note: Double labeled: green - Lgi4 reporter; red - Fabp7 (BFABP; assay MGI:5300955).
Structure Level Pattern Image Note
TS28: superior cervical ganglion Present Regionally restricted 2C mut Glia Merged , 2C mut Glia LacZ Expressed in glial cells.
Specimen 2C Neuron: postnatal adult; Lgi4tm1Sjm/Lgi4+ (more )
Note: Double labeled: green - Lgi4 reporter; red - Rbfox3 (assay MGI:5300959).
Structure Level Pattern Image Note
TS28: superior cervical ganglion Present Regionally restricted 2C mut Neuron Merged , 2C mut Neuron LacZ Expressed in glial cells, not neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory