Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Oxr1-cre)C14Stl
Name:	transgene insertion C14, Susumu Tonegawa
MGI ID:	MGI:5300944
Synonyms:	p(Oxr1-Cre)
Transgene:	Tg(Oxr1-cre)C14Stl  Location: unknown
Alliance:	Tg(Oxr1-cre)C14Stl page

Strain of Origin:

C57BL/6NTac

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Oxr1-cre)C14Stl expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Oxr1   Mutation details: The cre recombinase sequence was inserted by BAC recombineering methods into the translation initiation site in exon 2 of the Oxr1 gene in a BAC construct which contained the promoter region, coding sequence and a 50 kb 3' downstream region. The final vector was injected into pronuclei of fertilized C57BL/6 eggs. 16 founders were obtained and crossed with lacZ reporter mice to identify one line which displayed robust recombination in superficial layer III the dorsal portion of the medial entorhinal cortex. (J:178297)

Activity:	Tissue activity of this recombinase allele
Driver:	Oxr1 (species not specified) Summary of all recombinase alleles driven by Oxr1. Comparative matrix view of recombinase activities

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:178297 Suh J, et al., Entorhinal cortex layer III input to the hippocampus is crucial for temporal association memory. Science. 2011 Dec 9;334(6061):1415-20
All:	5 reference(s)