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Gene Expression Data
Assay Details
Assay
Reference: J:86049 Gavalas A, et al., Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes. Development. 2003 Dec;130(23):5663-79
Assay type: RNA in situ
MGI Accession ID: MGI:5300173
Gene symbol: Cdh8
Gene name: cadherin 8
Probe: Cad8 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6C: embryonic day 12.5 (more )
Note: This specimen is flat-mounted.
Structure Level Pattern Image Note
TS20: hindbrain Present Non-Uniform 6C Expression is present in the ventral half of rhombomeres 1, 2 and 3. There is also a longitudinal stripe of expression adjacent to the floor plate of rhombomeres 1 and 2 (but not 3).
TS20: facial ganglion Present 6C
TS20: trigeminal ganglion Absent 6C
Specimen 6D: embryonic day 12.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc (more )
Note: This specimen is flat-mounted.
Structure Level Pattern Image Note
TS20: hindbrain Present 6D The expression seen in the wild-type rhombomere 3 has expanded caudally in the mutant. The expansion is variable and not always the same on the left versus right side.
TS20: facial ganglion Absent 6D
Specimen 6E: embryonic day 12.5; Hoxb1tm1Brd/Hoxb1tm1Brd (more )
Note: This specimen is flat-mounted.
Structure Level Pattern Image Note
TS20: hindbrain Present Non-Uniform 6E Expression is ectopically expressed in rhombomere 4 in a pattern reminiscent of rhombomere 2.
TS20: facial ganglion Absent 6E
Specimen 6F: embryonic day 13.5 (more )
Note: This specimen is flat-mounted.
Structure Level Pattern Image Note
TS21: hindbrain Present Non-Uniform 6F Expression is present in the ventral half of rhombomeres 1, 2 and 3. There is also a longitudinal stripe of expression adjacent to the floor plate of rhombomeres 1, 2 and 3.
TS21: facial ganglion Present 6F
TS21: trigeminal ganglion Absent 6F
Specimen 6G: embryonic day 13.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc (more )
Note: This specimen is flat-mounted.
Structure Level Pattern Image Note
TS21: hindbrain Present 6G The expression seen in the wild-type rhombomere 3 has expanded caudally in the mutant. The expansion is variable and not always the same on the left versus right side.
TS21: facial ganglion Trace 6G
Specimen 6H: embryonic day 13.5; Hoxb1tm1Brd/Hoxb1tm1Brd (more )
Note: This specimen is flat-mounted.
Structure Level Pattern Image Note
TS21: hindbrain Present Non-Uniform 6H Expression is ectopically expressed in rhombomere 4 in a pattern reminiscent of rhombomere 2.
TS21: facial ganglion Absent 6H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory