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Gene Expression Data
Assay Details
Assay
Reference: J:86049 Gavalas A, et al., Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes. Development. 2003 Dec;130(23):5663-79
Assay type: RNA in situ
MGI Accession ID: MGI:5300171
Gene symbol: Lhx4
Gene name: LIM homeobox protein 4
Probe: Lhx4 cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4A: embryonic day 14.5; Hoxb2tm1Fmr/Hoxb2+ (more )
Note: This specimen is flat-mounted.
Structure Level Pattern Image Note
TS22: facial ganglion Present 4A
TS22: trigeminal ganglion Present 4A
TS22: cranial ganglion Present 4A Expression is present in the abducens nuclei.
TS22: hindbrain Present Non-Uniform 4A Expression is present in the nucleus ambiguus and dorsal rhombomere 4/5-derived notoneurons (future superior salivatory nucleus).
Specimen 4B: embryonic day 14.5; Hoxb2tm1Fmr/Hoxb2tm1Fmr (more )
Note: This specimen is flat-mounted.
Structure Level Pattern Image Note
TS22: facial ganglion Present 4B Expression in the mutant is reduced relative to that seen in wild type.
TS22: hindbrain Present Regionally restricted 4B There is also ectopic expression in a dorsal population of nuclei.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory