Gene Expression Data
Assay Details
Assay
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Reference:
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J:86049
Gavalas A, et al., Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes. Development. 2003 Dec;130(23):5663-79
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5300171
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Gene symbol:
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Lhx4
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Gene name:
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LIM homeobox protein 4
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Probe:
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Lhx4 cDNA4
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
4A:
embryonic day 14.5; Hoxb2tm1Fmr/Hoxb2 +
(more )
Note: This specimen is flat-mounted.
Specimen
4A:
(close )
Genetic Background:
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involves: 129
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Mutant Allele(s):
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Hoxb2tm1Fmr/Hoxb2+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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This specimen is flat-mounted.
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Specimen
4B:
(close )
Genetic Background:
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involves: 129
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Mutant Allele(s):
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Hoxb2tm1Fmr/Hoxb2tm1Fmr
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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This specimen is flat-mounted.
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Structure |
Level |
Pattern |
Image |
Note |
TS22: facial ganglion |
Present |
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4B
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Expression in the mutant is reduced relative to that seen in wild type.
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TS22: hindbrain |
Present |
Regionally restricted |
4B
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There is also ectopic expression in a dorsal population of nuclei.
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