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Gene Expression Data
Assay Details
Assay
Reference: J:86049 Gavalas A, et al., Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes. Development. 2003 Dec;130(23):5663-79
Assay type: RNA in situ
MGI Accession ID: MGI:5300084
Gene symbol: Hoxb2
Gene name: homeobox B2
Probe: Hoxb2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1E: embryonic day 10.5 (more )
Note: The specimen is flat-mounted.
Structure Level Pattern Image Note
TS17: hindbrain Present Non-Uniform 1E Expression is present in a series of longitundinal stripes.
TS17: rhombomere 4 Present 1E Expression is stronger in these rhombomeres, where it is upregulated in specific ventral and dorsal columns.
TS17: rhombomere 5 Present 1E Expression is stronger in these rhombomeres, where it is upregulated in specific ventral and dorsal columns.
TS17: rhombomere 6 Present 1E Expression is stronger in these rhombomeres, where it is upregulated in specific ventral and dorsal columns.

Specimen 1F: embryonic day 11.5 (more )
Note: The specimen is flat-mounted.
Structure Level Pattern Image Note
TS19: hindbrain Present Non-Uniform 1F Expression is present in a series of longitundinal stripes. In rhombomeres 4, 5 and 6, expression is upregulated in specific ventral and dorsal columns. Expression in the ventral domain resolved into two adjacent stripes.

Specimen 1G: embryonic day 12.5 (more )
Note: The specimen is flat-mounted.
Structure Level Pattern Image Note
TS20: hindbrain Present Non-Uniform 1G Expression was absent in a ventral territory corresponding to the path of facial branchial motoneuron migration.

Specimen 1H: embryonic day 13.5 (more )
Note: The specimen is flat-mounted.
Structure Level Pattern Image Note
TS21: hindbrain Present Non-Uniform 1H Expression is downregulated throughout the hindbrain.

Specimen 1D: embryonic day 14.5 (more )
Note: The specimen is flat-mounted.
Structure Level Pattern Image Note
TS22: hindbrain Present Non-Uniform 1D Expression is upgregulated in a region close to the final position of the facial motor nucleus.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory