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Gene Expression Data
Assay Details
Assay
Reference: J:71996 Selleri L, et al., Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation. Development. 2001 Sep;128(18):3543-57
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5298224
Gene symbol: Pbx1
Gene name: pre B cell leukemia homeobox 1
Antibody: anti-Pbx1b
Results
Specimen 2A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: embryo mesenchyme Present Diffuse 2A Diffuse nuclear expression in epidermis and mesenchymal tissues.
TS21: epidermis Present Diffuse 2A Diffuse nuclear expression in epidermis and mesenchymal tissues.
Specimen 2B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: rib cartilage condensation Strong 2B Most intense expression in mesenchyme condensing to form rib and vertebral cartilage.
TS21: rib pre-cartilage condensation Strong 2B Most intense expression in mesenchyme condensing to form rib and vertebral cartilage.
TS21: vertebral cartilage condensation Strong 2B Most intense expression in mesenchyme condensing to form rib and vertebral cartilage.
Specimen 2C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: rib cartilage condensation Strong Regionally restricted 2C Abundant expression in proliferating rib chondrocytes.
Specimen 2C inset: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: rib cartilage condensation Present Regionally restricted 2C inset Authors report nuclear expression.
Specimen 2D: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: rib Absent 2D Expression undetectable in hypertrophic chondrocytes.
Specimen 3A E11: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: 1st branchial groove ectoderm Present Regionally restricted 3A E11 Nuclear expression in the ectomesenchyme and ectoderm of the second branchial arch and around the first pharyngeal groove.
TS18: 2nd branchial arch ectoderm Present Regionally restricted 3A E11 Nuclear expression in the ectomesenchyme and ectoderm of the second branchial arch and around the first pharyngeal groove.
TS18: 2nd branchial arch mesenchyme derived from neural crest Present Regionally restricted 3A E11 Nuclear expression in the ectomesenchyme and ectoderm of the second branchial arch and around the first pharyngeal groove.
TS18: 1st branchial arch mandibular component mesenchyme derived from neural crest Weak Regionally restricted 3A E11 Lower nuclear expression in the ectomesenchyme of the mandibular and maxillary arches.
TS18: 1st branchial arch maxillary component mesenchyme derived from neural crest Weak Regionally restricted 3A E11 Lower nuclear expression in the ectomesenchyme of the mandibular and maxillary arches.
Specimen 3A E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: head mesenchyme Present Diffuse 3A E13.5 Authors report expression in the mesenchyme of the second branchial arch and first pharyngeal groove.
Specimen 4A Pbx1b wt: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb Absent 4A Pbx1b wt
Specimen 4A Pbx1b -/-: embryonic day 11.5; Pbx1tm1Mlc/Pbx1tm1Mlc (more )
Structure Level Pattern Image Note
TS19: limb Absent 4A Pbx1b -/-
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory