Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pglyrp3tm1Rdz
Name:	peptidoglycan recognition protein 3; targeted mutation 1, Roman Dziarski
MGI ID:	MGI:5297106
Gene:	Pglyrp3  Location: Chr3:91921890-91938889 bp, + strand  Genetic Position: Chr3, 40.14 cM, cytoband F1
Alliance:	Pglyrp3tm1Rdz page

Germline Transmission:	Earliest citation of germline transmission: J:178054
Parent Cell Line:	iTL1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2 through 5 were replaced with a neo cassette. Quantitative RT-PCR confirmed the absence of transcript expression. (J:178053, J:178054)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pglyrp3 Mutation:	22 strains or lines available

Original:	J:178054 Saha S, et al., PGLYRP-2 and Nod2 are both required for peptidoglycan-induced arthritis and local inflammation. Cell Host Microbe. 2009 Feb 19;5(2):137-50
All:	6 reference(s)