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Gene Expression Data
Assay Details
Assay
Reference: J:14717 Parr BA, et al., Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development. 1993 Sep;119(1):247-61
Assay type: RNA in situ
MGI Accession ID: MGI:5297048
Gene symbol: Wnt1
Gene name: wingless-type MMTV integration site family, member 1
Probe: Wnt1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6A: embryonic day 8.0 (more )
Note: This embryo is at the 4 somite stage.
Structure Level Pattern Image Note
TS12: future midbrain Present 6A

Specimen 6B: embryonic day 8.0 (more )
Note: This embryo is at the 4 somite stage.
Structure Level Pattern Image Note
TS12: future midbrain Present Regionally restricted 6B There is a broad dorsal to ventral distribution of expression, with the exception of the ventral midline.

Specimen 6C: embryonic day 8.5 (more )
Note: This embryo is at the 9 somite stage.
Structure Level Pattern Image Note
TS13: future midbrain Present Widespread 6C
TS13: future spinal cord Present 6C Initial expression is seen.

Specimen 6D: embryonic day 8.5 (more )
Note: This embryo is at the 9 somite stage.
Structure Level Pattern Image Note
TS13: future midbrain Present Non-Uniform 6D Anterior/rostral midbrain expression is decreasing, while more caudal/dorsal expression remains strong.

Specimen 6E: embryonic day 9.0 (more )
Note: This embryo is at the 15 somite stage.
Structure Level Pattern Image Note
TS14: future diencephalon Strong Regionally restricted 6E There is strong dorsal midline expression.
TS14: future spinal cord Strong Regionally restricted 6E There is strong dorsal midline expression.
TS14: future hindbrain Absent 6E No expression is present at the dorsal midline in the metencephalon, although it is present elsewhere in the hindbrain.
TS14: future midbrain Present Non-Uniform 6E Extensive dorsal to ventral expression is evident in the caudal midbrain, while ventral expression is weak in the anterior midbrain.

Specimen 6F: embryonic day 9.5 (more )
Note: This embryo is at the 27 somite stage.
Structure Level Pattern Image Note
TS15: central nervous system Present Regionally restricted 6F Expression is present along the dorsal midline from the diencephalon through the spinal cord, as well as in a ventral area in the caudal diencephalon.
TS15: diencephalon Present Regionally restricted 6F Expression is present along the dorsal midline from the diencephalon through the spinal cord, as well as in a ventral area in the caudal diencephalon.
TS15: future spinal cord Present Regionally restricted 6F Expression is present along the dorsal midline from the diencephalon through the spinal cord, as well as in a ventral area in the caudal diencephalon.
TS15: future hindbrain Present Regionally restricted 6F No expression is present in the metencephalon, although it is present elsewhere in the hindbrain.
TS15: future midbrain Present Non-Uniform 6F There is strong dorsal midline expression; weak, transient expression just lateral to the ventral midline; and a circle of expression just anterior to the mid/hindbrain junction (excluding the extreme ventral midline).

Specimen 7A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube roof plate Present 7A Expression is present at the dorsal midline.
TS15: future hindbrain Present Regionally restricted 7A Expression is present at the dorsal midline, although not in the metencephalon.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory