Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Dysftm2.1Kcam
Name:	dysferlin; targeted mutation 2.1, Kevin P Campbell
MGI ID:	MGI:5296776
Gene:	Dysf  Location: Chr6:83985572-84188042 bp, + strand  Genetic Position: Chr6, 36.14 cM
Alliance:	Dysftm2.1Kcam page

Germline Transmission:	Earliest citation of germline transmission: J:101977
Parent Cell Line:	W4 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette flanked by FRT sites was introduced to intron 53 in reverse transcriptional orientation along with a single loxP site. A second loxP site was placed in exon 54. The floxed fragment was deleted cre-mediated recombination, leaving the FRT-flanked neomycin cassette intact. (J:101977)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dysf Mutation:	183 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	1 reference(s)