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Gene Expression Data
Assay Details
Assay
Reference: J:152230 Takatalo MS, et al., Novel Golgi protein, GoPro49, is a specific dental follicle marker. J Dent Res. 2009 Jun;88(6):534-8
Assay type: RNA in situ
MGI Accession ID: MGI:5296330
Gene symbol: Dipk2a
Gene name: divergent protein kinase domain 2A
Probe: GoPro49 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 1A: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: tooth mesenchyme Present Regionally restricted 1A Expression was detected in the peripheral cells of the dental mesenchyme, but not in the forming dental papilla.

Specimen 1C: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: dental sac Present Regionally restricted 1C Expression was detected in the dental follicle.

Specimen 1E: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: dental sac Present Regionally restricted 1E Expression was detected in the dental follicle.

Specimen 1G & H & I: postnatal day 4 (more )
Note: Figs. 1H and 1I are higher magnification of the boxed areas in Fig. 1G.
Structure Level Pattern Image Note
TS28: dental sac Present Regionally restricted 1G , 1H , 1I Expression was detected in the labial and lingual sides of the incisor dental follicle and in the molar follicle.
TS28: jaw bone Weak 1H , 1G

Specimen 2B: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: dental sac Strong Regionally restricted 2B Expression was detected in the dental follicle.
TS28: stellate reticulum Present Regionally restricted 2B Expression was detected in the stellate reticulum of the first molar.
TS28: alveolar process Weak Regionally restricted 2B Expression was detected in osteoblasts throughout the alveolar bone.

Specimen 2E: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: dental sac Present Regionally restricted 2E Expression was detected in a large cluster of cells in the dental follicle mesenchyme at the site of initial root formation.

Specimen 2H & 2K: postnatal day 12 (more )
Note: Fig. 2K is a higher magnification of 2H.
Structure Level Pattern Image Note
TS28: dental sac Present Regionally restricted 2K , 2H Expression was detected in the dental follicle and most prominent in the root follicle. Expression was reduced compared to earlier stages.
TS28: periodontal ligament Present Regionally restricted 2H , 2K There was some expression in the periodontal ligament along the root.

Specimen Appendix 2C & 2D: postnatal day 7 (more )
Note: Appendix Fig. 2D is a higher magnification of 2C.
Structure Level Pattern Image Note
TS28: stellate reticulum Present Regionally restricted Appendix 2C Expression was detected in the stellate reticulum of the first molar in an area near the dental lamina.
TS28: dental sac Present Regionally restricted Appendix 2D , Appendix 2C Expression was detected in the dental follicle at the junction between the crown and root.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory