Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ddctm1.1Rhrs
Name:	dopa decarboxylase; targeted mutation 1.1, Raymond Harris
MGI ID:	MGI:5296328
Synonyms:	Aadcflox7
Gene:	Ddc  Location: Chr11:11764101-11848144 bp, - strand  Genetic Position: Chr11, 7.09 cM, cytoband A1-A4
Alliance:	Ddctm1.1Rhrs page

Germline Transmission:	Earliest citation of germline transmission: J:175630
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 7. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 7. Flp-mediated recombination removed the neo cassette and left exon 7 floxed. (J:175630)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ddc Mutation:	126 strains or lines available

Original:	J:175630 Zhang MZ, et al., Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice. J Clin Invest. 2011 Jul 1;121(7):2845-54
All:	5 reference(s)