Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Krt15-cre/ERT2)CNiem
Name:	transgene insertion C, Catherin Niemann
MGI ID:	MGI:5296325
Synonyms:	C_K15CreERhigh
Transgene:	Tg(Krt15-cre/ERT2)CNiem  Location: unknown
Alliance:	Tg(Krt15-cre/ERT2)CNiem page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Krt15-cre/ERT2)CNiem expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Krt15   Mutation details: A 5 kb Krt15 promoter fragment was inserted into a vector containing the cre/ERT2 (Cre/ER(G)T2) cassette. The construct was microinjected into oocytes and eight founder lines were obtained. 3 lines were found to exhibit specific cre nuclear staining patterns and recombined reporter patterns (in offspring of crosses) in hair follicles after tamoxifen administration. A high expressing line, line C, was established. (J:175633)

Activity:	Tissue activity of this recombinase allele
Driver:	Krt15 (species not specified) Summary of all recombinase alleles driven by Krt15.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:175633 Petersson M, et al., TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis. EMBO J. 2011;30(15):3004-18
All:	2 reference(s)