Tg(Chrna1)1Ekr
Transgene Detail
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| Symbol: |
Tg(Chrna1)1Ekr |
| Name: |
transgene insertion 1, Ellen Kraig |
| MGI ID: |
MGI:2447080 |
| Transgene: |
Tg(Chrna1)1Ekr Location: unknown
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| Alliance: |
Tg(Chrna1)1Ekr page
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| Strain of Origin: |
Not Applicable
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Chrna1)1Ekr expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| electric ray, Pacific |
Chrna1 |
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Mutation details: The chicken Chrna1 promoter was used to drive expression of Torpedo californica (fish) Chrna1 cDNA in muscle tissue. The transgene construct included a spliceable intron and polyadenylation sequences from the rabbit beta globin gene. Only one founder line was generated. Transgene expression was verified by RT-PCR analysis with strong expression observed in muscle tissue. Very low levels of transgene expression was observed in the brain and thymus.
(J:80567)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:80567 Stacy S, et al., Split tolerance in a novel transgenic model of autoimmune myasthenia gravis. J Immunol. 2002 Dec 1;169(11):6570-9 |
| All: |
3 reference(s) |
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Analysis Tools
