Gene Expression Data
Assay Details
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Assay
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Reference:
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J:148991
Barkic M, et al., The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival. Mol Cell Biol. 2009 May;29(10):2489-504
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5295369
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Gene symbol:
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Trp53
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Gene name:
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transformation related protein 53
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Antibody:
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Anti-p53
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Results
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Specimen
2A wt:
embryonic day 6.5
(more  )
Specimen
2A wt:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 6.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS9: embryo |
Absent |
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2A wt
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Specimen
2A L24 Bst/+:
embryonic day 6.5; Rpl24Bst/Rpl24 +
(more )
Specimen
2A L24 Bst/+:
(close )
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Genetic Background:
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B6.BKS-Rpl24Bst
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Mutant Allele(s):
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Rpl24Bst/Rpl24+
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Age:
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embryonic day 6.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS9: embryo |
Present |
Widespread |
2A L24 Bst/+
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Expression was detected in a great majority of cells in the mutant embryo.
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Specimen
2B wt:
embryonic day 7.5
(more )
Specimen
2B wt:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: embryo |
Absent |
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2B wt
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Specimen
2B L24 Bst/+:
embryonic day 7.5; Rpl24Bst/Rpl24 +
(more )
Specimen
2B L24 Bst/+:
(close )
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Genetic Background:
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B6.BKS-Rpl24Bst
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Mutant Allele(s):
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Rpl24Bst/Rpl24+
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: embryo |
Present |
Widespread |
2B L24 Bst/+
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Expression was detected in the majority of cells in the mutant.
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Specimen
not shown:
embryonic day 8.5; Rpl24Bst/Rpl24 +
(more )
Specimen
not shown:
(close )
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Genetic Background:
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B6.BKS-Rpl24Bst
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Mutant Allele(s):
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Rpl24Bst/Rpl24+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: embryo |
Present |
Regionally restricted |
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In the mutant, expression was upregulated in all embryonic tissues except the primitive heart.
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| TS13: heart |
Absent |
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Specimen
3D wt:
embryonic day 10.5
(more )
Specimen
3D wt:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: embryo |
Ambiguous |
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3D wt
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Specimen
3D L24 Bst/+:
embryonic day 10.5; Rpl24Bst/Rpl24 +
(more )
Specimen
3D L24 Bst/+:
(close )
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Genetic Background:
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B6.BKS-Rpl24Bst
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Mutant Allele(s):
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Rpl24Bst/Rpl24+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
S3A wt:
embryonic day 10.5
(more )
Specimen
S3A wt:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Absent |
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S3A p53 wt
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There was no expression in the retina.
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Specimen
S3A L24 Bst/+:
embryonic day 10.5; Rpl24Bst/Rpl24 +
(more )
Specimen
S3A L24 Bst/+:
(close )
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Genetic Background:
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B6.BKS-Rpl24Bst
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Mutant Allele(s):
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Rpl24Bst/Rpl24+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Absent |
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S3A p53 L24 Bst/+
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There was no expression in the retina as in wild type.
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Specimen
S3B wt:
embryonic day 11.5
(more )
Specimen
S3B wt:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: retina |
Absent |
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S3B p53 wt
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Specimen
S3B L24 Bst/+:
embryonic day 11.5; Rpl24Bst/Rpl24 +
(more )
Specimen
S3B L24 Bst/+:
(close )
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Genetic Background:
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B6.BKS-Rpl24Bst
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Mutant Allele(s):
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Rpl24Bst/Rpl24+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: retina |
Absent |
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S3B p53 L24 Bst/+
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Specimen
S4A wt:
embryonic day 11.5
(more )
Specimen
S4A wt:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: embryo |
Absent |
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S4A p53 wt
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Specimen
S4A L24 Bst/+:
embryonic day 11.5; Rpl24Bst/Rpl24 +
(more )
Specimen
S4A L24 Bst/+:
(close )
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Genetic Background:
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B6.BKS-Rpl24Bst
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Mutant Allele(s):
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Rpl24Bst/Rpl24+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: heart |
Present |
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S4A p53 L24 Bst/+
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| TS19: liver |
Present |
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S4A p53 L24 Bst/+
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| TS19: neural tube |
Present |
Regionally restricted |
S4A p53 L24 Bst/+
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Expression was detected in the posterior part of the neural tube.
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Specimen
4A wt Thymus:
postnatal week 6
(more )
Specimen
4A wt Thymus:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: thymus |
Absent |
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4A p53 wt Thymus
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Specimen
4A L24 Bst/+ Thymus:
postnatal week 6; Rpl24Bst/Rpl24 +
(more )
Specimen
4A L24 Bst/+ Thymus:
(close )
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Genetic Background:
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B6.BKS-Rpl24Bst
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Mutant Allele(s):
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Rpl24Bst/Rpl24+
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: thymus |
Absent |
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4A p53 L24 Bst/+ Thymus
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Specimen
4A wt Spleen:
postnatal week 6
(more )
Specimen
4A wt Spleen:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: spleen |
Absent |
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4A p53 wt Spleen
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Specimen
4A L24 Bst/+ Spleen:
postnatal week 6; Rpl24Bst/Rpl24 +
(more )
Specimen
4A L24 Bst/+ Spleen:
(close )
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Genetic Background:
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B6.BKS-Rpl24Bst
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Mutant Allele(s):
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Rpl24Bst/Rpl24+
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: spleen |
Absent |
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4A p53 L24 Bst/+ Spleen
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Specimen
4A wt S. intestine:
postnatal week 6
(more )
Specimen
4A wt S. intestine:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
4A L24 Bst/+ S. intestine:
postnatal week 6; Rpl24Bst/Rpl24 +
(more )
Specimen
4A L24 Bst/+ S. intestine:
(close )
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Genetic Background:
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B6.BKS-Rpl24Bst
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Mutant Allele(s):
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Rpl24Bst/Rpl24+
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
4A wt Kidney:
postnatal week 6
(more )
Specimen
4A wt Kidney:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
4A L24 Bst/+ Kidney:
postnatal week 6; Rpl24Bst/Rpl24 +
(more )
Specimen
4A L24 Bst/+ Kidney:
(close )
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Genetic Background:
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B6.BKS-Rpl24Bst
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Mutant Allele(s):
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Rpl24Bst/Rpl24+
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
4A wt Liver:
postnatal week 6
(more )
Specimen
4A wt Liver:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: liver |
Absent |
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4A p53 wt Liver
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Specimen
4A L24 Bst/+ Liver:
postnatal week 6; Rpl24Bst/Rpl24 +
(more )
Specimen
4A L24 Bst/+ Liver:
(close )
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Genetic Background:
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B6.BKS-Rpl24Bst
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Mutant Allele(s):
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Rpl24Bst/Rpl24+
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: liver |
Absent |
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4A p53 L24 Bst/+ Liver
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Analysis Tools