Tg(Bmi1-cre/ERT2)1Fjs
Transgene Detail
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| Symbol: |
Tg(Bmi1-cre/ERT2)1Fjs |
| Name: |
transgene insertion 1, Frederick J de Sauvage |
| MGI ID: |
MGI:5294806 |
| Synonyms: |
Bmi1CreER |
| Transgene: |
Tg(Bmi1-cre/ERT2)1Fjs Location: unknown
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| Alliance: |
Tg(Bmi1-cre/ERT2)1Fjs page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Bmi1-cre/ERT2)1Fjs expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Bmi1 (MGI:88174) |
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Mutation details: A BAC (RP23-181D14) containing the Bmi1 locus was modified via recombineering methods by insertion of an IRES-cre/ERT2-pA-Frt-neo-Frt cassette at 85 base pairs 3' of the stop codon of Bmi1. The neo cassette was deleted by transforming the modified BAC into arabinose-induced cells expressing Flp. The final vector was injected into C57BL/6 blastocysts to generate germline-transmitting mice.
(J:177145)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Bmi1
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:177145 Tian H, et al., A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature. 2011 Oct 13;478(7368):255-9 |
| All: |
1 reference(s) |
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Analysis Tools
