Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Myh6-TRPC6*)1Jmol
Name:	transgene insertion 1, Jeffery D Molkentin
MGI ID:	MGI:5294560
Synonyms:	dnTRPC6
Transgene:	Tg(Myh6-TRPC6*)1Jmol  Location: unknown
Alliance:	Tg(Myh6-TRPC6*)1Jmol page

Strain of Origin:

FVB

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(Myh6-TRPC6*)1Jmol expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human TRPC6 (7225) Trpc6  (MGI:109523)   Mutation details: The mouse Myh6 promoter drives expression of human TRPC6 cDNA in which three highly conserved amino acids (L678-W680) within the putative pore region have been replaced by alanine (A) residues. Line 1 was generated. (J:177257)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:177257 Hofmann T, et al., Subunit composition of mammalian transient receptor potential channels in living cells. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7461-6
All:	1 reference(s)