Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Myh6/tetO-ATP2B4)1Jmol
Name:	transgene insertion 1, Jeffery D Molkentin
MGI ID:	MGI:5294558
Transgene:	Tg(Myh6/tetO-ATP2B4)1Jmol  Location: unknown
Alliance:	Tg(Myh6/tetO-ATP2B4)1Jmol page

Strain of Origin:

FVB

Transgene Type:    Transgenic (Inducible, Inserted expressed sequence) Inducer:    doxycycline/tetracycline Mutation:    Insertion   Tg(Myh6/tetO-ATP2B4)1Jmol expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human ATP2B4 (493) Atp2b4  (MGI:88111)   Mutation details: Human ATP2B4 cDNA (also known as PMCA4b) and a tetracycline-responsive promoter element (tetO) were fused to the cardiac-specific alpha myosin heavy chain (Myh6) mouse promoter. Line 1 was generated. (J:149624)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:149624 Wu X, et al., Plasma membrane Ca2+-ATPase isoform 4 antagonizes cardiac hypertrophy in association with calcineurin inhibition in rodents. J Clin Invest. 2009 Apr;119(4):976-85
All:	1 reference(s)