Tg(ACTA1-Atp2a1)1Jmol Transgene Detail MGI Mouse (MGI:5294556)

Tg(ACTA1-Atp2a1)1Jmol
Transgene Detail

Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Summary

Symbol:	Tg(ACTA1-Atp2a1)1Jmol
Name:	transgene insertion 1, Jeffery D Molkentin
MGI ID:	MGI:5294556
Transgene:	Tg(ACTA1-Atp2a1)1Jmol Location: unknown
Alliance:	Tg(ACTA1-Atp2a1)1Jmol page

Transgene
origin

Strain of Origin:

FVB

Transgene
description

Transgene Type:

Transgenic (Inserted expressed sequence)

Mutation:

Insertion

Tg(ACTA1-Atp2a1)1Jmol expresses 1 gene

Mutation details: A transgenic vector was designed to express the rat skeletal muscle isoform of SERCA1 (Atp2a1) cDNA under the regulatory control of a human skeletal alpha actin (ACTA1) promoter. (J:171822)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

Original:	J:171822 Goonasekera SA, et al., Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. J Clin Invest. 2011 Mar 1;121(3):1044-52
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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